Daily birth control pill for men shows promise, says UW study

Contraceptive Pills For Men Will Become A Reality As The Trials Revealed Positive Results

A once-a-day contraceptive pill for men is a step closer to approval after early tests show it to be both safe and effective, according to researchers. The pill contains the activities of male hormone testosterone and also a female hormone progestin.

Nonetheless, it may be the best hope yet for a non-permanent male contraceptive, said Stephanie Page of the University of Washington School of Medicine. Page explained that although the blood levels of the male hormones dipped, there were no symptoms of testosterone deficiency or excess. DMAU is developed by the National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development, that also sponsored this study. She added that an effective oral contraceptive for men was hard to produce until now, due to the rapid metabolization rates of androgenous hormones by the male body.

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Poole's 3-pointer as the clock expired turned a two-point deficit into a one-point victory that propelled MI into the Sweet 16. Wagner and Abdur-Rahkman both finished with 12 for the Wolverines (30-7), while Charles Matthews finished his night with 11.

However, all the men taking the male pill had weight gain and a drop in their HDL or good cholesterol levels. All of the men took the pills once per day with food for 28 days. Known as dimethandrolone undecanoate, or DMAU, research was presented at Chicago's annual Endocrine Society meeting that a month-long trial was recently completed with positive results.

A daily pill for males has always been elusive to pharmaceutical developers, as oral testosterone in previous forms may damage the liver or clear the body too quickly to work in just one pill per day. The researchers have discovered that a 400 mg dose of DMAU is enough to lower the male hormones involved in sperm production without affecting the sex drive. "Testosterone production is blocked and therefore sperm are not able to finish their last stages of maturation", she said. Mood and sexual functions too remained unaltered with this pill, Page said.

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One big question has always been whether men would actually take a birth control pill reliably, since they're not the ones who bear the burden of pregnancy. All passed safety tests including those suggestive of liver and kidney health, a hurdle previous attempts at male contraceptives have failed to meet. One of the major downsides of this medical innovation - and something which had been an issue before 1960 as well - is that women are often expected to deal with birth control by themselves.

As it was acknowledged that further studies are needed to gauge whether the new contraceptive for men can truly be effective in actual use, the researchers hope to determine in the future whether the drug affects sperm count for a span of three months.

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Recent clinical tests on a male contraceptive pill have yielded successful results, possibly suggesting that a once-a-day oral contraceptive option might soon join injections and gels among the birth control options for men.

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